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Frances E Jensen Selected Research

2,3- dioxo- 6- nitro- 7- sulfamoylbenzo(f)quinoxaline (NBQX)

1/2018Early Seizures Prematurely Unsilence Auditory Synapses to Disrupt Thalamocortical Critical Period Plasticity.
11/2013AMPA receptor antagonist NBQX attenuates later-life epileptic seizures and autistic-like social deficits following neonatal seizures.
1/2013Gene expression profiling of a hypoxic seizure model of epilepsy suggests a role for mTOR and Wnt signaling in epileptogenesis.
3/2005AMPA/kainate receptor-mediated downregulation of GABAergic synaptic transmission by calcineurin after seizures in the developing rat brain.
6/2004NBQX or topiramate treatment after perinatal hypoxia-induced seizures prevents later increases in seizure-induced neuronal injury.

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Frances E Jensen Research Topics

Disease

34Seizures (Absence Seizure)
01/2022 - 06/2002
17Hypoxia (Hypoxemia)
01/2018 - 06/2002
11Epilepsy (Aura)
02/2016 - 04/2008
9Periventricular Leukomalacia (Neonatal Cerebral Leukomalacia)
04/2015 - 04/2002
7Brain Injuries (Brain Injury)
01/2017 - 06/2002
6Ischemia
03/2016 - 06/2002
5Tuberous Sclerosis (Bourneville's Disease)
04/2012 - 05/2007
2Alzheimer Disease (Alzheimer's Disease)
01/2022 - 01/2020
2Temporal Lobe Epilepsy
01/2020 - 01/2018
2Intellectual Disability (Idiocy)
12/2019 - 11/2011
2Autism Spectrum Disorder
01/2018 - 03/2016
2Status Epilepticus (Complex Partial Status Epilepticus)
08/2015 - 05/2014
2Drug Resistant Epilepsy
05/2014 - 04/2012
2Brain Hypoxia (Cerebral Hypoxia)
01/2013 - 04/2009
2Autistic Disorder (Autism)
01/2012 - 11/2011
1Amyloid Plaque
01/2020
1Cognitive Dysfunction
01/2020
1CDKL5 deficiency disorder
12/2019
1Rare Diseases (Rare Disease)
12/2019
1Rett Syndrome (Rett's Disorder)
01/2018
1Brain Diseases (Brain Disorder)
03/2016
1Congenital Heart Defects (Congenital Heart Defect)
10/2015
1Hypothermia
06/2015
1Nervous System Diseases (Neurological Disorders)
05/2014
1Medulloblastoma
04/2014
1Neoplasms (Cancer)
04/2014
1Encephalitis (Encephalitis, Rasmussen)
02/2014
1Focal Cortical Dysplasia
04/2012
1Rodent Diseases
02/2012
1Inborn Genetic Diseases (Disease, Hereditary)
11/2011

Drug/Important Bio-Agent (IBA)

12Anticonvulsants (Antiepileptic Drugs)IBA
02/2016 - 06/2004
8AMPA Receptors (AMPA Receptor)IBA
12/2019 - 05/2004
7Glutamate Receptors (Glutamate Receptor)IBA
01/2015 - 06/2002
5Bumetanide (Bumex)FDA LinkGeneric
01/2021 - 11/2005
52,3- dioxo- 6- nitro- 7- sulfamoylbenzo(f)quinoxaline (NBQX)IBA
01/2018 - 06/2004
5TOR Serine-Threonine KinasesIBA
03/2016 - 04/2008
5Kainic Acid (Kainate)IBA
05/2014 - 05/2004
4Proteins (Proteins, Gene)FDA Link
01/2021 - 01/2013
4alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA
05/2014 - 06/2002
4Glutamic Acid (Glutamate)FDA Link
05/2014 - 06/2002
4trans-sodium crocetinate (crocetin)IBA
04/2012 - 05/2007
3Sirolimus (Rapamycin)FDA Link
01/2022 - 11/2011
3Mechanistic Target of Rapamycin Complex 1IBA
01/2022 - 01/2012
3Phenobarbital (Luminal)FDA Link
01/2021 - 04/2011
3N-Methylaspartate (NMDA)IBA
01/2015 - 11/2011
3gamma-Aminobutyric Acid (GABA)IBA
05/2014 - 03/2005
3Biomarkers (Surrogate Marker)IBA
02/2014 - 07/2009
2Amyloid (Amyloid Fibrils)IBA
01/2022 - 01/2020
2Pentylenetetrazole (Metrazol)IBA
01/2022 - 08/2015
2Pharmaceutical PreparationsIBA
01/2021 - 01/2020
2Phosphotransferases (Kinase)IBA
01/2020 - 03/2013
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2015 - 06/2015
2Member 2 Solute Carrier Family 12IBA
04/2015 - 01/2013
2N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
05/2014 - 06/2008
2Levetiracetam (Keppra)FDA LinkGeneric
01/2013 - 11/2006
2Oxygen (Dioxygen)IBA
07/2009 - 05/2003
2Glucose (Dextrose)FDA LinkGeneric
07/2009 - 05/2003
2Kainic Acid Receptors (Kainate Receptor)IBA
03/2005 - 05/2004
2Topiramate (Topamax)FDA LinkGeneric
06/2004 - 05/2004
1Actin Depolymerizing Factors (Cofilins)IBA
01/2021
1EnzymesIBA
01/2020
1JNK Mitogen-Activated Protein KinasesIBA
01/2020
1AntibodiesIBA
01/2020
1Peptides (Polypeptides)IBA
01/2020
1Protein Kinases (Protein Kinase)IBA
01/2020
1IEM 1460IBA
12/2019
1Cyclin-Dependent Kinases (cdk Proteins)IBA
12/2019
1Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA
01/2018
1Transcription Factors (Transcription Factor)IBA
01/2018
1Methyl-CpG-Binding Protein 2IBA
01/2018
1CystathionineIBA
01/2017
170-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA
01/2017
1CalciumIBA
10/2016
1Fragile X Mental Retardation ProteinIBA
03/2016
1Lorazepam (Ativan)FDA LinkGeneric
08/2015
1ChloridesIBA
04/2015
1A-factor (Streptomyces)IBA
04/2015
1Messenger RNA (mRNA)IBA
05/2014
1lestaurtinibIBA
05/2014
1Tyrosine Kinase InhibitorsIBA
05/2014
1GABA Receptors (GABA Receptor)IBA
05/2014
1Small Interfering RNA (siRNA)IBA
04/2014
1Biological ProductsIBA
04/2014
1Neurotransmitter Receptors (Neurotransmitter Receptor)IBA
04/2014
1AutoantibodiesIBA
02/2014
1EpitopesIBA
02/2014
1AMPA 1 glutamate receptor ionotropicIBA
12/2012
1Serine (L-Serine)FDA Link
12/2012
1Brain-Derived Neurotrophic Factor (BDNF)IBA
01/2012
1Doxycycline (Periostat)FDA LinkGeneric
11/2011
1NestinIBA
11/2011
1fluoro jadeIBA
04/2011
1Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA
11/2010

Therapy/Procedure

9Therapeutics
01/2022 - 11/2006
1Transcranial Direct Current Stimulation
08/2015
1Drug Therapy (Chemotherapy)
04/2014
1Hemispherectomy
02/2014
1Transcranial Magnetic Stimulation
02/2012
1Anesthesia
02/2012
1Electrodes (Electrode)
04/2011